Endocrine Abstracts

Clinical outcome and Implications for training in thyroid surgery in a district general HospitalAuthors: Rajashekhar Rao, Kanagaraj Marimuthu, and Paul ThomasObjective: To assess the volume of work outcome and training opportunity in adistrict general Hospital and compare with the BAES recommendationsMethods: Retrospective study, Patients identified by theatre records, pathology<p c...

Background: It is widely believed that increased circulatory concentrations of long-chain saturated fatty acids (LC-SFA) significantly contribute to the death and dysfunction of pancreatic β-cells in the development of type 2 diabetes (T2D). The mechanism by which LC-SFA cross the β-cell plasma membrane has not been fully established. This work aims to characterise the mechanism underpinning this uptake. Ultimately, regulation of LC-SFA entry may maintain β-cell...

A retrospective analysis of the results of all intra-arterial calcium stimulations performed at St. Vincent’s Hospital, Dublin, in the years 2001-2006. All patients with symptoms suggestive of hypoglycemia had 72 hour fasting test with evidence of inappropriately elevated insulin and c-peptide at the time of hypoglycemia. These patients were investigated further with pancreatic imaging and selective intra-arterial calcium stimulation with hepatic venous sampling (ASVS). A...

One of the hallmarks of parturition in most mammals is a dramatic drop in plasma levels of progesterone (P4), which promotes myometrial relaxation, prior to labor. In humans and some other primates however, the opposite occurs and placental P4 production increases with advancing pregnancy. The expression of nuclear progesterone receptor (PR)-responsive genes is decreased in the primate uterus at term, which suggests ‘functional’ progestin withdrawal involves repressi...

The presence of lipomas is a characteristic of the syndrome of multiple endocrine neoplasia type 1. The presence of myxomas, however, is a characteristic of Carney syndrome.The aim of the study is the description of a patient with the syndrome of multiple endocrine neoplasia type 1 who presented with a malignant angiomyxoma.A male patient, aged 42 years, presented with intense gastric complaints and was diagnosed with a gastroduode...